Brief Content of Lecture Series :

Review of Mathematical Concepts - Statistics, Sequences,Matrixes and graphs, Introduction to Nucleotides, Amino acids, Proteins, Genes, Introns, Exons and their relationship, Introduction to the organization of a genome, Introduction to string matching alogrithms, Database search techniques, Sequence comparison and alignment techniques, Use of Biochemical scoring matrixes, Introduction to graph matching algorithms, Automated genome comparison and its implication, Automated gene predication, Automated identification of bacterial operons and pathways, Genome evolution analysis- Distance matrix and phylogenetic tree, lateral gene transfer, gene insertion/deletion, Specific and Conserved Genes, Protein structure predication, protein folding, Case study of a complete bacterial genome, cloning and Expressed Sequence Tags, cDNA libraries, SNP (Single Nucleotide polymorphism), Gene Arrays, Analysis of gene arrays, Time series analysis, Introduction to data mining, application of gene arrays, Time application of Bio-informatics to inhibitors and drug design, Introduction of flux analysis in pathways, Any other recent topic/current issues of interest.